CMU MEMS Laboratory Publication Abstract

 

in Technical Proceedings of the Fifth International Conference on Modeling and Simulation of Microsystems (MSM), pp. 182-185, April 22-25, 2002, San Juan, Puerto Rico.
Dispersion Modeling in Microfluidic Channels for System-Level Optimization
B. Baidya, T. Mukherjee and J. Hoburg
ABSTRACT:
Chip-based microfluidic separation systems often use serpentine channels to achieve long separation lengths in minimal area. Such designs suffer from the 'racetrack' effect due to the bends in the microchannel. In addition, the skew produced by a bend cannot be undone by an equal and opposite bend due to non-axial diffusion occurring in the inter-turn straight channel. This paper analyzes the non-axial diffusion of skewed bands of solute, in electrokinetic microchannels containing turns, to develop models which can be used for a system-level optimization of such designs. Distortion caused by transition and wall effects in the turn geometry and the inter-turn channel are also analyzed. Finite volume simulations are used to verify the proposed theory. Keywords: turn induced dispersion, non-axial diffusion, effective diffusivity, electrokinetic separation, microfluidics, micro total analysis systems
© 2002 Computational Publications. Abstracting is permitted with credit to the source. Other copying, reprint or repoduction requests should be addressed to: Copyrights Manager, Computational Publications, Copyright Office, 899 Rue Jean de Gingins, 01220 Divonne les Bains, France. Computational Publications is a subsuduary of the Applied Computational Researh Society, a non-profit organization
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